Trabecular Angiomyolipoma Mimicking Hepatic Cell Carcinoma

Eszter SZÉKELY1, Zsuzsa SCHAFF2, Lilla MADARAS1, Péter KUPCSULIK3, Attila ZSIRKA3

12nd Department of Pathology, Semmelweis University, Budapest, Hungary
21st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
31st Department of Surgery, Semmelweis University, Budapest, Hungary


Hepatic angiomyolipomas are rare tumors, especially in comparison with those occurring in the kidney. Nevertheless, it is important to be aware of their existence, especially when occurring in the liver, where they might have different subtypes. Not infrequently they are composed of rather irregular cells with epithelioid appearance. In these cases hepatocellular carcinoma or the possibility of other malignant tumors has to be ruled out, with the aid of numerous immunohistochemical reactions. The authors present a case of a female patient, whose liver lesion was first diagnosed on cytological examination as a hepatocellular carcinoma. Based on the preoperative cytological diagnosis, a large liver lobe resection was performed. Histological examination found an angiomyolipoma of the above-mentioned type, and the final diagnosis was ascertained with the aid of vimentin, smooth muscle actin (SMA), and HMB-45. Pathology & Oncology Research, Vol 6, Nr 3, 224-226, 2000

Key words: hepatic tumor; angiomyolipoma; trabecular; epithelioid

Received: Dec 9, 1999; accepted: Jul 22, 2000
Correspondence: Eszter SZÉKELY, 2nd Department of Pathology, Semmelweis University, Üllôi út 93 Budapest H-1091, Hungary; Tel: (36-1) 215-0185, Fax: (36-1) 215-6921; E-mail:

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