PATHOLOGY & ONCOLOGY RESEARCHVol. 7 No. 1, 2001

 Report

Composite Pituitary Adenoma and Intrasellar Tuberculoma

Report of a Rare Case

Mehar Chand SHARMA1, Sandeep VAISH2, Reena ARORA1, Sailesh GAIKWAD3, Chitra SARKAR1

1Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
2Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India
3Department of Neuroradiology, All India Institute of Medical Sciences, New Delhi, India

 

Tuberculous involvement of the pituitary gland is rare. We report a unique case of a composite lesion consisting of pituitary adenoma and intrasellar tuberculoma. A 24-year-old lady presented with features of acromegaly and amenorrhea. Serum growth hormone levels were found to be raised. Radiological investigations were consistent with a pituitary adenoma. Decompression of the lesion was done through trans-sphenoidal approach. Histological examination revealed a growth hormone secreting pituitary adenoma in association with a granulomatous lesion suggesting of pituitary tuberculoma. No other evidence of tuberculosis was found in the brain or spinal cord. This type of dual pathology has been reported only once in the earlier literature. Pathology & Oncology Research, Vol 7, Nr 1, 74-76, 2001

Key words: adenoma; endocrine; pituitary gland; sella; tuberculoma


Received: Jul 13, 2000; accepted: Jan 17, 2001
Correspondence: Chitra SARKAR, Department of Pathology, All India Institute of Medical Sciences, New Delhi 110029, India; Tel: 91-11-659 3371, Fax: 91-11-686 2663; E-mail: sarkarch@medinst.ernet.in

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