Synovial Sarcoma: a Rare Tumor of Larynx

Bilge BILGIC1, Özgür METE1, Settar A ÖZTÜRK1, Misten DEMIRYONT1, Nesil KELES2, Mert BASARAN3

1Department of Pathology, Istanbul Medical Faculty, Istanbul, Turkey
2ENT Surgery, Istanbul Medical Faculty, Istanbul, Turkey
3Medical Oncology Oncology Institute, Istanbul University, Istanbul, Turkey


Synovial sarcoma is a soft tissue sarcoma of unknown histogenesis and occurs predominantly in the lower extremities of young adults. The head and neck is a relative rare location. There are about 10 cases with laryngeal localization in the literature. We present a 24 year-old male with an endolaryngeal mass. Incisional biopsy and the hemilaryngectomy material revealed a biphasic synovial sarcoma. One year later a local recurrence occurred. Tumor excision and neck dissection were performed. Radiotherapy was added. Six months later lung metastases was discovered on thoracic CT. The patient received chemotherapy for 6 courses. The metastases responded well to chemotherapy and the patient is now alive without tumor on radiological and clinical examination after 3.5 years of follow-up. Pathology & Oncology Research, Vol 9, Nr 4, 242-245, 2003

Key words: larynx; synovial sarcoma

Received: May 6, 2003; accepted: Nov 12, 2003
Correspondence: Bilge BILGIC, Department of Pathology, Istanbul Medical Faculty, Istanbul 34390, Turkey, Fax: 0 212 6311367; E-mail:

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