PATHOLOGY & ONCOLOGY RESEARCHVol. 3 No. 1, 1997

 Article

Changing Pattern of Bladder Cancer Cytology (Haynal Imre University Experience)

Ferenc KISS1, Ferenc SALAMON1, József RÓZSAHEGYI2

1Institute of Pathological Anatomy, Haynal Imre University of Health Sciences, Budapest, Hungary
2Department of Urology, Haynal Imre University of Health Sciences, Budapest, Hungary

 

Urinary cytology reports of 151 patients with histologically verified tumors from the periods 1981-1985 and 1991-1995 were analyzed. No significant change in the overall sensitivity of tumor detection (76% and 76.8%, respectively) was found. In the group of well-differentiated (G0-G1) tumors, however, 60% of the more recent cases were cytologically positive or suspicious, 23% more than ten years ago. A decrease in the detection rate of G2 tumors in the last period (72% versus 89%) was probably caused by false negative reports due to frequent inflammatory changes in the specimens. Poorly differentiated (G3-G4) transitional cell tumors resulted in a high rate of positive cytological diagnoses (93% in both periods). In cases with negative cytology at clinical suspicion of tumor, repeated sampling increased the detection rate of G0-G1 lesions from 53% up to 60%. Optimal sampling and preparation technique, cytopathologists training and improved follow-up of patients are preconditions of sensitive and specific urinary cytology. Pathology & Oncology Research, Vol 3, Nr 1, 47-50, 1997

Key words: urinary cytology; sensitivity; transitional cell neoplasms


Received: Sep 15, 1996; accepted: Nov 22, 1996
Correspondence: Ferenc KISS, Institute of Pathological Anatomy, Haynal Imre University of Health Sciences, 2nd Institute of Pathology, Üllõi út 93. Budapest , Hungary; Tel: (36)(1)2157300, Fax: (36)(1)2156921; E-mail: kf@korb2.sote.hu

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