PATHOLOGY & ONCOLOGY RESEARCHVol. 3 No. 2, 1997

 Report

Malignant Mixed Mullerian Tumor of the Extra-genital Coelomic Epithelium: Report of Two Cases

Irene G IBANEZ-MANLAPAZ1, David MCCOY2, Vincent III VINCENT3, Ulla Jo ULE4

1Department of Pathology, St. Frances Cabrini Hospital, Louisiana, USA
2Department of Surgery, St. Frances Cabrini Hospital, Louisiana, USA
3Department of Obstetrics & Gynecology, St. Frances Cabrini Hospital, Louisiana, USA
4Department of Medicine, St. Frances Cabrini Hospital, Louisiana, USA

 

Malignant mixed mullerian tumors of the extra-genital coelomic epithelium (female peritoneum) are rare. Since the first case report in 1955, only nineteen have been described. In our Case 1 a 58 year-old G3P3 (gravidity = 3; parity = 3) white female with mixed mullerian tumor, homologous type, involving the abdominal peritoneum was treated with surgery and chemotherapy (doxorubicin hydrochloride and cis-platinum). She died of the disease 20 months after initial surgery. Case 2 is a 75 year-old G0P0 (gravidity = 0; parity = 0) white female with mixed mullerian tumor containing heterologous elements involving the pelvic peritoneum who was treated with surgery and chemotherapy (ifosfamide with mesna). She relapsed 6 months after surgery and refused any further treatment. She died 2 weeks later. These cases support the fact that malignant mixed mullerian tumor of the female peritoneum is rare and usually affects elderly females. It has poor prognosis and among the 15 reported cases with follow-up indicating time and presence of disease at death, only 5 survived more than 12 months after initial surgery. Pathology & Oncology Research, Vol 3, Nr 2, 130-134, 1997

Key words: extra-genital mullerian tumor; carcinosarcoma; poor prognosis; female peritoneum


Received: Feb 10, 1997; accepted: Apr 5, 1997
Correspondence: Irene G IBANEZ-MANLAPAZ, Department of Pathology, St. Frances Cabrini Hospital, 3330 Masonic Drive Louisiana 71301, USA; Tel: (318)4486740, Fax: (318)4486825

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