Current Management of AIDS Related Non Hodgkin's Lymphoma

Kathryn FIFE1, Mark BOWER2

1Medical Oncology Unit, Charing Cross Hospital, London, UK
2Kobler Center, Chelsea & Westminster Hospital, London, UK


Non Hodgkin's lymphoma is the AIDS defining illness in 3-3.5% of patients and is increasing in incidence as the survival of HIV infected people improves. The incidence of these intermediate/high grade B cell malignancies is sixty times higher than in the general population. The most important prognostic factors are a CD4 positive lymphocyte count of <100 cells/mm3, a prior AIDS defining diagnosis, an ECOG performance status >2 and primary cerebral origin. Patients with any of these factors are most likely to benefit from palliative rather than radical treatment. Good prognosis patients have a 30-40% chance of cure from their lymphoma with carefully administered intensive chemotherapy. Pathology & Oncology Research, Vol 2, Nr 4, 272-275, 1996

Key words: AIDS; Non-Hodgkin's lymphoma

Received: Oct 2, 1996; accepted: Oct 20, 1996
Correspondence: Kathryn FIFE, Medical Oncology Unit, Charing Cross Hospital, Fulham Palace Road London W6 8RF, UK; Tel: 0181-8461419, Fax: 0181-8461443; E-mail:

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