PATHOLOGY & ONCOLOGY RESEARCHVol. 4 No. 1, 1998

 Report

Biclonal primary plasma cell leukemia

Zoltán TÓTH, József SIPOS

Department of Pathology, County Hospital of Zala, Zalaegerszeg, Hungary

 

Authors present a multiparameter pathological study in a case of rapid biclonal primary plasma cell leukemia. The immunohistochemical data revealed aberrant phenotypes (monocyte, epithelial and T-cell) probably in connection with microenvironmental influences. Biclonality can be attributed to class switching during malignant transformation. Static image cytometry showed aneuploidy. The blasts of this process are active immunoregulatory cells. Pathology & Oncology Research, Vol 4, Nr 1, 48-51, 1998

Key words: primary plasma cell leukemia; biclonality; immunohistology; image cytometry


Received: Dec 28, 1997; accepted: Feb 8, 1998
Correspondence: Zoltán TÓTH, Department of Pathology, County Hospital of Zala, Zrínyi út 1. Zalaegerszeg H-8901, Hungary

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