PATHOLOGY & ONCOLOGY RESEARCHVol. 10 No. 3, 2004

 Article

Estrogen Receptor Expression in Salivary Gland Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma

Fábio Ramôa PIRES1, Danyel Elias da Cruz PEREZ2, Oslei Paes DE ALMEIDA2, Luiz Paulo KOWALSKI3

1Oral Pathology, School of Dentistry, State University of Rio de Janeiro, Rio de Janeiro, Brazil
2Oral Pathology, School of Dentistry of Piracicaba, State University of Campinas, Piracicaba, Brazil
3Department of Head and Neck Surgery and Otorhinolaryngology, AC Camargo Cancer Hospital, Sao Paulo, Brazil

 

Estrogen receptor (ER) expression in salivary gland carcinomas is controversial, and most published studies considered no more than 10 cases. We analyzed ER expression by immunohistochemistry in 136 mucoepidermoid carcinomas and 72 adenoid cystic carcinomas. All cases were negative. These results do not support a role for estrogens in salivary gland mucoepidermoid carcinoma and adenoid cystic carcinoma. Pathology & Oncology Research, Vol 10, Nr 3, 166-168, 2004

Key words: mucoepidermoid carcinoma; adenoid cystic carcinoma; salivary gland tumors; immunohistochemistry; estrogen; estrogen receptor


Received: Apr 9, 2004; accepted: Aug 20, 2004
Correspondence: Luiz Paulo KOWALSKI, Department of Head and Neck Surgery and Otorhinolaryngology, AC Camargo Cancer Hospital, Rua Prof Antônio Prudente, 211, Liberdade Sao Paulo 01509-900, Brazil; Tel: +55-11-3341-0325, Fax: +55-11-3277-6789; E-mail: lp_kowalski@uol.com.br

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