Improving Diagnostic Accuracy of Prostate Carcinoma by Systematic Random Map-biopsy

János SZABÓ1, György HEGEDÛS1, Katalin BARTÓK2, Tibor KERÉNYI3, Attila VÉGH1, Imre ROMICS4, Béla SZENDE5

1Department of Urology, Central Military Hospital, Budapest, Hungary
2Department of Pathology, Central Military Hospital, Budapest, Hungary
32nd Institute of Pathology, Semmelweis University, Budapest, Hungary
4Department of Urology, Semmelweis University, Budapest, Hungary
5Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary


Systematic random rectal ultrasound directed map-biopsy of the prostate was performed in 77 RDE (rectal digital examination) positive and 25 RDE negative cases, if applicable. Hypoechoic areas were found in 30% of RDE positive and in 16% of RDE negative cases. The score for carcinoma in the hypoechoic areas was 6.5% in RDE positive and 0% in RDE negative cases, whereas systematic ''map” biopsy detected 62% carcinomas in RDE positive, and 16% carcinomas in RDE negative patients. The probability of positive diagnosis of prostate carcinoma increased in parallel with the number of biopsy samples/case. The importance of systematic map biopsy is emphasized. Pathology & Oncology Research, Vol 6, Nr 2, 111-113, 2000

Key words: map-biopsy; prostate; carcinoma; RDE

Received: Feb 10, 2000; accepted: Apr 10, 2000
Correspondence: Béla SZENDE, Institute of Pathology and Experimental Cancer Research, Semmelweis University, Üllõi út 26. Budapest H-1085, Hungary; Tel: 36-1-266-0451, Fax: 36-1-317-1074; E-mail:

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